Of Brain Stems and Witches: Ghost Pipe

UPDATE:  Hello friends!  Many folks in the herbal community are becoming increasingly concerned about ethical wildcrafting and human carelessness when wild harvesting plants for medicine. Ghost Pipe in particular is a vulnerable creature and Sean Donahue has written eloquently about how we humans can do damage both accidentally and on purpose. Please check out his post in addition to what I’ve offered here. It’s good to know this plant, and its good to refrain from its medicine if feel we don’t have its full blessing. If its possible for your body and life structures, venturing out and sitting at the feet of the wild-growing medicines will not only help you learn what the plant teaches, but help us understand the anti-materialist practices and potential of energetic and subtle-body medicine.

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There is a lot of lore and and witchy writing out there about this succulent and eerie little creature, and I am no more immune to its draw than the next plant nerd. This summer I’ve been quite aware of the small clusters of these nodding flowers as they observe my human doings en route to the swimming spot or napping in the hemlock groves.

If you’ve never sat with Ghost Pipe, allow me to describe how it grows with two or twelve companions in stands no more than ten inches high, clustered through damp acidic coniferous groves and often in companionship with Ganoderma (Reishi) and Mitchella (Partridge Berry). The waxy paleness of the plant earned it the common name Corpse Plant in New England, for the little fist that some think reaches from a grave, bruising a swift black when brushed against. Alice Morse Earle wrote in the early 19th centurey that Ghost Pipe is “the weirdest flower that grows, so palpably ghastly that we feel almost a cheerful satisfaction in the perfection of its performance and our own responsive thrill.” We give so many names to what we don’t understand, both poetic and explanatory: Ice Plant, Wax Plant, Convulsion Weed, Fit Plant, Death Plant.

ghostpipe7For further proof of the queer witchiness of this plant, I present you Emily Dickenson. It appears she retained a personal relationship with the Ghost Flower from childhood, and when her neighbor gifted her with a watercolor of the plant, Dickenson’s thank you letter contained tones of metaphysical shock: “That without suspecting it you should send me the preferred flower of life, seems almost supernatural… I still cherish the clutch with which I bore it from the ground when a wondering child, and unearthly booty, and maturity only enhances the mystery, never decreases it.”

Oh my.  Are you not convinced? Come meet this herb.

 

BOTANY & BIOGEOGRAPHY

ghostpipe2The latin binomial Monotropa uniflora indicates that a single flower grows terminally on an upright stalk in one direction, with the flower drooping its head over until it begins making seed. Monotropa uniflora is one of two species in its entire genus, its cousin being Monotropa hypopithys, or Pinesap, a similarly strange but far more colorful inhabitant of the. Formerly understood as a saprophyte which did not require chlorophyll for photosynthesis but rather took nutrients from decaying matter in the soil, Monotropa uniflora is now thought of as an epiparasite or mycoheterophyte known to survive in complex relationship with mycorrhizal fungi in the soil, which in turn interact with the neighboring photosynthesizing plants in a biome, usually the roots of a living tree such as beech, hemlock, or cedar. While the Ghost Pipe is thought to be primarily parasitic, the fungi in the soil form beneficial symbiotic relationships with the trees and shrubs, assistance in producing necessary sugars for the tree.

Dr. Ryan Drum explains this all so well:

Indian pipe, ghost plant, is a remarkable botanical curiosity as well as a powerful nervine. 
It is a mysterious, underground except when flowering, perennial common boreal non-photosynthetic 
flowering epiparasite. It parasitizes parasitic tree fungi, and is not dependent on one particular
 fungus, forming associations with at least a dozen different fungi, many of which produce edible 
mushrooms. It grows in complete shade on stable forest floors, usually where green plants do not. 
It seems completely dependent on its host fungi for organic nutrients. Its underground mass attracts 
fungal mycelial growth, from the fungi parasitizing live trees, both conifers and deciduous trees, 
providing myriad small knobbly papillar surfaces where nutrients pass from the fungal tissue to Monotropa. 
At least 14 species of trees can be used. I do not know if an individual Monotropa plant utilizes 
more than one fungal species or more than one tree species. I assume that the fungi derive some benefit from their associations with Monotropa, probably derivative secondary metabolites.

In his lovely writing on this epiparasite, Sean Donahue offers energetic observations of the plant based on its growth patterns, noting that while trees pass information and energy in a linear, centralized-library sort of stream between roots and branches, the network of mycelium and roots that Monotropa is tapped into allows for multi-directional, diffused, decentralized exchange. This interdependent physiology mirrors human neural networks, while the tender white tissues of each Ghost Pipe plant strangely resemble the structure of the mammalian brainstem. What can be seen here is the way that Monotropa interacts with the human nervous system, able to interpret, reorder and modulate large or chaotic amounts of information and stimuli.

Also, a note on herbivory: nothing seems to consider this plant a food staple.

 

PHARMACOLOGY & SPECIFIC INDICATIONS

ghostpipe11Monotropa uniflora emerges unobtrusively from the ground, quiet and still as a Greek chorus with some unanticipated piece of information on the tip of its tongue. The flowers erect and tender spines appear to hold each other up in their alignment, encouraging the clumps to hold its structure despite each plant’s delicacy and causing the herbalist to train the eyes to detect the upright patterning in the chaos of the leaf litter.

In a most general way, this profound nervine offers an quieting or cooling to an heated nervous states; older physio-medicalist texts and European documentation of First Nations traditional broadly describe the use of the herb for pain and neurological disruptions, such as seizures, convulsions, insomnia, extreme mental states, and regular muscular spasming. Felter and Lloyd, in the 1898 King’s American Dispensatory specify periodic fevers, childhood (febrile) seizures, elipectic seizures, opthamological inflammation, bladder inflammation. Most useful to me, however, have been the specific conditions or states for which the use of this plant are indicated.

I find it important to remember that Monotropa is able to help mediate both internal and external environments, whether the sensory imput comes from inside or outside us, whether it is physical or emotional. In my mind, Monotropa is the acute trauma relief precursor to Milky Oats’ tonic trauma support, creating the initial space that Milky Oats is later able to fill in a long-term nourishing way. Ghost Pipe seems to offer an aligning, re-regulating, reordering, and soothing of a chaotic mind or unmanageable pain.

ghostpipe10David Winston writes that Ghost Pipe is “not your normal analgesic.” Many people report the experience of taking this herb while experiencing strong physical pain and, while the pain does not go away, the individual is less attached to the pain, able to tolerate it, often feeling that they are standing beside it and watching it happen. Winston says this is called “antinociceptive,” meaning that the herb “reduces sensitivity to painful stimuli” and “raises the threshold for pain.” The same is true for emotional or psychologically painful situations, in which the person suffering is able experience relief from the intensity and to examine the experience with a little bit of spaciousness, a degree of separation. Sometimes, an individual experiences chronic or regular nervous dysregulation, either through painful autoimmune situations or extreme psychiatric states.

SPECIFIC INDICATIONS

+ Intense pain that interferes with ability to sleep 
+ Painful conditions in which the individual needs to remain awake, grounded, present 
+ Physical or emotional pain that is overwhelming 
+ Pain that is paralyzing due to overload of sensory information, psycho-emotional shock 
+ Anxiety or panic attack due to emotional or sensory overload 
+ Headaches caused by traumatic brain injury 
+ Acute psychiatric states, PTSD

PAIRINGS

+ Monotropa and Crataegus berry: vascular pressure from rebound trauma, brusing (Drum) 
+ Monotropa and Sea Blush Roots (Plectritis congesta, a marine valerian): acute psychiatric conditions (Drum) 
+ Monotropa and Canabis: unmanagable chronic pain (Donahue) 
+ Monotropa, Staychys betonica, Clematis: headaches from traumatic brain injury (Donahue) 
+ Monotropa and Anemone: anxiety, panic attack (Donahue) 
+ Monotropa, Stachys betonica, Acorus Calamus, Ocimum sanctum: PTSD, triggering experience, disassociation, feeling stuck in memory of trauma (Donahue)

 

HOW TO USE THIS MEDICINEghostpipedead3

Dr. Drum notes that, while the plant’s flowering time depends on moisture, temperature, and fungal growth in the soils, the peak flowering time in much of North America appears to be July. Harvest gently to avoid bruising, wash debris away gently, tincture immediately. Flowers and roots could be used separately; using aerial parts only is advocated by Sean Donahue as most sustainable. The tincturing process results in a dark purple-black extract and a rich flavor. One friend of mine seems to think it tastes like vanilla and cinnamon. I have experimented on myself and friends according to both Donahue’s and Drum’s recommendations for dosing, which advise starting with 3 drops and increasing dose to 30 drops upon observation of reaction. For acute states, it is possible to administer or take up to 1 ml at 5 minute intervals. Dr. Drum notes that 15 ml of more can induce a deep sleep with strange, vivid, and sometimes erotic dreaming.

Be forewarned.

 

 

SOURCES

Donahue, Sean. Ghost Pipe: A Little Known Herb. American Herbalists Guild. http://www.americanherbalistsguild.com/sites/default/files/donahue_sean_-_ghost_pipe-_a_little_known_nervine.pdf

Zdenka Babikova, Lucy Gilbert, Toby J. A. Bruce, Michael Birkett, J

ohn C. Caulfield, Christine Woodcock, John A. Pickett, David Johnson. “Underground signals carried through common mycelial networks warn neighbouring plants of aphid attack.” Ecology Letters. (2013)

16: 835–843. Retrieved from http://onlinelibrary.wiley.com/

Harvey Wickes Felter and John Uri Lloyd. King’s American Dispensatory. 1898. Retrieved from http://www.henriettesherbal.com/eclectic/kings/monotropa.html

David Winston. Ghost Pipe. Facebook post. February 24, 2012.

Drum, Ryan, PhD. “Three Herbs: Yarrow, Queen Anne’s Lace, and Indian Pipe.” Retrieved from http://www.ryandrum.com/threeherbs.htm

 

 

 

 

 

 

 

 

Nice to Meet You, Aralia nudicaulis

I’m quite excited about the Aralia family. Of this family, I’m most acquainted with the elusive Panax quinqufolius, the five-leaved friend American ginseng (thanks to my time at the United Plant Savers Sanctuary), and the stately larger cousin Aralia racemosa, or Spikenard, although I have had brief lucky occasions to meet another even larger cousin, Aralia californica, or California Spikenard.

IMG_0136
Aralia nudicaulis

Since I’ve been living in the northern hardwood forests of Vermont, I’ve been so curious about the smaller and commoner creature Aralia nudicaulis, confusingly called many adorable names including wild sarsaparilla, false sarsaparilla, shot bush, small spikenard, wild liquorice, and rabbit root. How, I’ve been wondering, does the smaller Aralis nudicaulis compare in its medicine?

 

 

BOTANY & BIOGEOGRAPHY

IMG_0182The North American Spikenards are in the Aralia or Ginseng Family (Araliaceae) and are closely related to the Apicaeae (Umbelliferae) family of Parsley and Carrot kin. The Aralias tend to have solid sturdy stems and succulent berries, ovate or egg-shaped leaves with slight serrations and fine pointed tips, delicate umbel-like flowers, and an overall elegance to their general profile. Traditionally thought to contain the strongest medicine, the root grows down directly from the stem for several inches into the soil and sends out secondary runners horizontally, from which new plants emerge, connecting the group through the forest floor. The dark purple-black fruit needs lots of moisture to germinate the seeds, however, which makes all Aralias most abundant in wet climates and far more particular about habitat than their more adaptable Carrot family relatives.

Herbalist Lisa Fazio of Hawthorne Hill Herbs offers a beautiful geographical-energetic picture (what she calls a “metaphysical pattern”) of the relationship of Aralia nudicaulis‘ growth pattern to its energetic actions:

[Aralia Nudicaulis] has roots (actually underground stems) that grow laterally. This signifies 
communication that is dispersed in a web of synapse alongside the mycelial network. This transmits 
information in a matrix that, instead of being concentrated up and down, is dispersed outward where 
it is less centered, more continuous and evenly distributed. . . This contiguity allows for easy 
networking from plant to plant providing steadily accessible nutrients, perception and expression. . . 
When standing among a patch, or really it’s a sea, of Wild Sarsparilla there is always a feeling 
of aliveness, awareness and alertness but without feeling over-stimulated, as if my cells are being 
provided just the precise amount of energy required that can be effectively metabolized and released. 

IMG_0170While the Aralia racemosa, which can grown to be as tall as my own five foot stature, seems to me to grow more solitarily in damp rich woods with sweeter soils, the knee-high Aralia nudicaulis seems slightly less picky, often making a thick layer in drier and more acidic soils amidst the fall of hemlock leaves. While digging Aralia racemosa is an undertaking for which I set aside at least an hour to unearth a good chunk of root and runner, Aralis nudicaulis feels like a less invasive harvest, where I can often dig from one out of every thirty plants I can see.IMG_0143

Michael Moore differentiates the Aralia genus into two distinct sorts of species, one with woods stems, acrid aromas, and spines (Aralia spinosa, or Devil’s Walkingstick) and the other which are the Aralia that we are presently mulling over, which are more characterized by juicier roots, herbaceous annual growth, a spicy sweet, cool and moist, and generally higher concentrations of saponins, aralosides, and ginsenosides. He loosely groups Aralia racemosa, Aralia nudicaulis, Aralia californica, and Aralia humulis, the last of which is primarily a creatures of the southwestern United States.

 

DIFFERENTIATING ARALIAS: ADAPTOGEN & PULMONARY MEDICINE

Aralias tend to have adaptogenic properties, which in Western herbalism most often means that this is an herbs which may have one or many of a broad array of tactics which assists the human in adapting to stress. In my experience, large Aralia racemosa is also a warming lung tonic which is helpful in the dampness of fall and winter in the southern climates. Other southern herbalists have expressed an opinion I share, which is that the larger and spicier spikenard possesses more adaptogenic properties than the smaller wild sarsaparilla. While many herbalists and researchers agree that the Spikenard Aralias overlaps in adaptogenic and respiratory actions, there is inevitable disagreement in how the specific indications for each species compare.

IMG_0134
Aralia nudicaulis

According to researchers Li, O’Neill, et al, in the Journal of Ethnopharmacology (2012), First Nations people of east Canada, including Algonquin and Iroquois people, were known to brew tea of the dried root of wild sarsaparilla for lung conditions including irritating mucous-producing coughs and tuberculosis. The researchers also noted that water extracts of the roots were show in laboratory trials to have antimycobacterial activity, which supports the use of this herb in combating the colonizing of fungus-like bacteria such as tuberculosis. Harvey and Felter, the physiomedicalists responsible for King’s American Dispensatory published in 1898, agreed that the racemosa and nudicaulis may be used similarly in cases of “pulmonary affections,” with specific indications for lax or “atonic” states of irritation and excess mucous in the respiratory tract.

Moore offers a broader usage that places Aralias in an adaptogen-like category, recommending them as long-term tonic herbs which “offer the Ginseng-like effects of modifying metabolic and emotional stresses.” He does, however, differentiate the specific indications for Aralia racemosa as more strongly pulmonary in application compared to the other three Aralias (as written in his Medicinal Plant Folios).

 

SPECIFIC INDICATIONS (Michael Moore, SWSBM)

Aralia Aralia californica, Aralia humilis, Aralia nudicaulis 
+ Adrenal cortex hypofunctions 
+ Blood serum levels: hyperlipidemia
Aralia racemosa 
+ Chronic coughing with excess secretions; bronchorrhea 
+ Chronic laryngitis with excess, abundant mucus 
+ Chronic pharyngitis with thick tenacious mucus
+ Chronic bronchitis with profuse secretions and debility 
+ Subacute cystitis with mucus in urine, no odor 
+ Adaptogen similar to Panax + Adrenal cortex hypofunctions 
+ Primipara, with irritability, distress in last trimester 
+ Subanemic blood with hypersensitivities

 

BLOOD TONICS & CANCER PREVENTION

Laboratory research loves to investigate cancer-inhibiting potential in herbal medicines — cancers are, after all, devastating conditions that significantly alter a person’s existence, and of course they offer lucrative opportunity to the medical, pharmaceutical, and nutriceutical industries.

Traditional use of “blood cleansing” herbs, however, supports the use of some herbs as cancer-preventing. In his writing on herbal first aid, Matthew Wood discusses the philosophy, held in many First Nations medicine traditions as well as in Chinese herbalism, that perceives certain conditions as “stagnant blood,” indicating sluggish or inadequate circulating and poorly oxygenated blood, predisposing the body toward cancerous growth. Angelica and sassafras have both been known for their blood-moving and alterative properties in such conditions.

IMG_0191Perhaps more specific and particular than categorizing wild sarsaparilla as adaptogenic is to understand it as an alterative which offers tonifying support to adrenal function. Lisa Fazio notes that Iroquois peoples used the Aralia nudicaulis as “blood medicine,” particularly for rheumatic and diabetic situations in which circulation was impeded and therefore allowing buildup in the blood of compound which should otherwise have been excreted. In her writing on Aralia nudicaulis, she notes the following specific indications:

+ Excess androgens, hormone dysregulation; acnes, PCOS 
+ Sluggish cellular metabolism 
+ Malnourished states; depletions of calcium, potassium, magnesium, iron, and zinc 
+ Tissue repair, including bone, connective tissue, arthritic conditions 
+ Inflammatory join conditions, particularly auto-immune conditions 
+ Deficiency conditions leading to muscle wasting, weight loss, and weakness

 

ROOTS & HONEY: HOW TO TAKE THE MEDICINE

IMG_0194I think my approach this coming fall in understanding this medicine is going to be through the lens of re-patterning and balancing. Whatever the bio-chemical or physiological actions of these roots on the lungs, adrenals, immune cells, or circulation, the humble and sturdy Aralia nudicaulis gently urges me toward in a sideways reach, as if for a helpful hand or to collaborate, to steadily keep moving and re-moving obstacles from the path of resilience, so that the cells and tissues and mysterious systems can go about doing what they do best.

IMG_0216Roots are best dug in the fall or spring, and then chopped and dried for a decoction or fresh tinctured in high-proof alcohol. Harvey and Felter recommends dosage of 5 to 30 drops of the tincture in water, given 4 times per day. I have had great success with infusing fresh chopped Aralia racemosa roots in raw honey; the outcome is spicy, sweet, and warming. If you try adding an Aralia nudicaulis honey to your apothecary shelf this fall, do write and tell me your experiences! I’ll write you back with mine.

 

SOURCES

Li H1, O’Neill T, Webster D, Johnson JA, Gray CA. Anti-mycobacterial diynes from the Canadian medicinal plant Aralia nudicaulis. J Ethnopharmacol. 2012 Mar 6;140(1):141-4. doi: 10.1016/j.jep.2011.12.048. Epub 2012 Jan 3.

Felter, H.W., and Lloyd, J.U. King’s American Dispensatory. 1898.

Moore, Michael. Plant Folios: Aralia, Spikenard. http://www.swsbm.com/FOLIOS/AraliFol.pdf

Fazio, Lisa. Hawthorne Hill Herbs. Aralia nudicaulis. http://www.hawthornehillherbs.com/node/227

Herrick, James. Iroquois Medical Botany.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

DEAR COPTIS

You know how a dog can be excited about the same darn ball over and over again, like every time you throw it for her its always the first time she’s ever had the opportunity to fetch anything at all?

I can be that way with plants, irrationally excited to see the same old friend who I just sat next to five minutes ago. It’s an especially prominent pattern for me up in these north woods, where I regularly meet botanical friends who are absent or uncommon in the Carolinas where I’m from.

Like Coptis.

coptispatch6The mere sight of Coptis (Coptis trifolia, Ranunculaceae) being its green, elegant, un-assuming self has offered proof this spring of the end of cold weather. This little herb has three delicate leathery leaves and fine yellow-gold threads for roots that connect shallowly in the soil, with a flower. I think the eclectic physicians Felter and Lloyd King’s American Dispensatory (1898) wax eloquent on the botanical identification of Coptis, and I’ve rearranged their description in a sort of stanza:

Rhizome, slender, creeping, bright yellow, branched

sending at intervals of four to six inches

clusters of leaves and flowers.

Leaves all radical in tufts, surrounded at base by yellowish scales;

Petiole slender, erect or reclining.

Leaves evergreen, veiny, firm, smooth, shining, palmately ternate

margins sharply, mucronately and crenately toothed,

Flowers, solitary, radical, white,

borne on a slender, erect scape and bearing, above the middle,

a single small bract.

Fruit, three to ten, dry membranous follicles,

slenderly stipitate at the base,

and tipped with the persistent curved style at the apex.

Seed five to ten,

small, horizontal, black.

Coptis aspleniifolia (spleenwort-leaf goldthread) and Coptis occidentalis  (Idaho goldthread) are popular herbs native to North America.  Traditionally the rhizome of this herb are the parts used medicinally. The gold indicates that this herb is one of several that contain berberine, a bright yellow-golds alkaloid that is strongly antimicrobial and soothing to inflamed tissues, famous in the treatment of bacterial, viral, fungal, yeast, and parasitic infections. I bet you’re familiar with other berberine-containing herbs, yes?

Oregon Grape (Berberis aquafolium)

Yellow Root (Xanthorrhiza simplississima)

Golden Seal (Hydrastis canadensis)

Japanese Barberry (Berberis thunbergii)

Chinese researchers Jing Liu, MD, PhD and Zhengwei He, PhD., note that coptis (Huang Lian, Coptis chinensis) is a widely used therapeutic ally in Chinese medicine, which recognizes 15 species in the genus. The ancient medical text the Divine Husband’s Classic of the Materia Medica is the first known description of the medicinal use of coptis in Chinese medicine, and it recognizes the prominent uses of the herb as heat-clearing, detoxifying, and dispelling dampness. In modern Chinese medical practice, Coptis is widely used for myriad infectious and inflammatory conditions.

coptis2
golden thread-like rhizomes of Coptis

The authors further note that in particular, recent research suggests the use of Coptis for acne, GI infection involving heliobater pylori bacteria, and conditions responding poorly to antibiotic treatment. Subhuti Dharmananda, PhD, who is the director of the Institute for Traditional Medicine in Portland, Oregon, observes that the damp-heat syndromes particularly relating to GI, respiratory, and skin infections are an indication for the use of berberine herbs. Dharmananda reports that berberines have been used successfully in modern chinese medicine to treat acude cases of gastoenteritis, cholera, and bacillary dysentery, and that lab trials have shown in vitro inhibition of giardia and candida growth upon berberine applications.

While reading about Coptis, I learned that current research shows berberine-containing herbs to be useful in the prevention and treatment of insulin resistance and diabetes, cardivoascular diseases, certain cancers, and perhaps even dementia.

coptisseed
Coptis going to seed

According to Dr. Julian Whitaker (http://www.whitakerwellness.com/health-concerns/diabetes-treatment/berberine-diabetes/), several threads of research indicate that an isolated berberine compound was found to be as effective as metformin, which is the most commonly proscribed drug for Type 2 Diabetes. He notes that in one clinical trial, diabetic patients with dyslipidemia (dysregulated cholesterol and triglycerides) who use a berberine supplement for three months resulted in blood sugar improvements that compared favorable with results from existing pharmaceuticals on the market. Dr. Whitaker goes on to explain how berberines work in the regulation of triglycerides and blood sugars.

“Berberine targets a very basic and ancient regulator of metabolism present in all animals and plants called AMP-activated protein kinase (AMPK).Activated by decreased ATP (energy) production, AMPK turns on multiple protective metabolic pathways to ensure survival in times of stress [. . .]”

Here are some of the things that AMPK does:

+ Increases insulin sensitivity by encouraging cells to take in    glucose

+ Reduces the production of glucose in the liver, which is overactive in people with diabetes

+ Slows down the release of free fatty acid, which in turn reduces serum lipid levels

+ Stimulates mitochondrial function, which in turn produces energy for the body

+ Lowers blood pressure and prevents atherosclerosis by release Nitrous oxide, which signals arteries to relax and open, increasing blood flow

+ Regulates cancerous proliferation by inhibitsing a biochemical pathway called mTORC1, which is cell-proliferative and inhibits normal cell death (apoptosis)

Pretty nifty, eh? Suddenly it seems worth the poking and wrestling required in an Oregon Grape patch in pursuit of those golden roots.

Some words of warning, of course. In ways similar to pharmaceutical antibiotics, I have seen berberines, and goldenseal in particular, become unhelpful in cases of infection when communities of people over-use or otherwise misuse berberine herbs. Microbes seem to be able to evolve defenses against these herbs similarly to presciption antibiotics. Matthew Wood, in a paper called “Herbal First Aide,” writes that goldenseal at one point became a “fad herb” for cuts and infections because of the popular idea that is a “natural antibiotic” that will kill the germs which might infect a wound. Wood warns that, although goldenseal might be appropriate to close up a clean bleeding wound in which we might want to sprinkle golden seal powder to prevent bacterial invasion, a wound that is already dirty and infected in not an appropriate occasion for goldenseal, which may seal the inflammation, pus, and infection in (similarly to comfrey) and cause systemic infection. Additionally, Jing and Zhenwei warn that research shows a potential interference of antioxiants like berberine with chemotherapy.

At the very least, go meet the little creature. She usually doesn’t bite when you pet her.

 

 

RESOURCES

Felter and Harvey. King’s American Dispensatory. (1898) (www.henriettes-herb.com/eclectic/kings/coptis.html)

Dr. Julian Whitaker. http://www.whitakerwellness.com/health-concerns/diabetes-treatment/berberine-diabetes/

Tan W, et al. Anti-cancer natural products isolated from Chinese medicinal herbs. Chin Med. 2011 Jul;6(1):27.

Yin J, et al. Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism. 2008 May;57(5):712–717.

Zhang Y, et al. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. J Clin Endocrinol Metab. 2008 Jul;93(7):2559––2565.

Jing Liu, MD, PhD; Zhengwei He, PhD. Rationale and Problems for Use of Coptis and Berberine in Cancer chemoprevention. N A J Med Sci. 2008;1(1):38-43.

Wood, Matthew, Herbal First Aide.